In Darksiders II: Deathinitive Edition, players take on the role of Death, or Strife, as they navigate through a vast, open world filled with puzzles, platforming sections, and intense combat. The game's story follows Death as he attempts to clear his brother War's name and reclaim his rightful place on the Council of Shadows. Along the way, players encounter a variety of characters, including other Horsemen, angels, and demons, each with their own agendas and motivations.