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Software for motif discovery and next generation sequencing analysis

HOMER (Hypergeometric Optimization of Motif EnRichment) is a suite of tools for Motif Discovery and ChIP-Seq analysis. It is a collection of command line programs for unix-style operating systems written in mostly perl and c++. Homer was primarily written as a de novo motif discovery algorithm that is well suited for finding 8-12 bp motifs in large scale genomics data.

Hardware Requirements (recommended): 2+ Gb memory (4-8+ Gb), 10+ Gb Hard Drive space (50+ Gb)
Software Requirements: Unix compatible OS (or cygwin), perl, gcc, make, wget (optional for full functionality: R, DESeq2, blat, bedGraphToBigWig, liftOver)
License: GPLv3

HOMER works on pretty much any Linux/UNIX systems, including MacOS (if Xcode compilers are installed) and on Windows using either cygwin or a Linux subsystem.

If you are looking specifically for HOMER2, you are in the right place! HOMER2 is integrated into HOMER.

Full Program Download

"The Ice Cream Man" is a heartwarming and humorous novel that follows the story of a beloved ice cream vendor who brings joy to the children of a small town. With his colorful truck and irresistible treats, he's a staple of summertime fun. But as the seasons change and the ice cream man faces challenges, he must confront his own demons and learn to adapt to a new reality. This poignant and uplifting tale explores themes of community, friendship, and the power of a simple pleasure.

Program Components and Older Versions

Icecandymanbookfreedownload | Exclusive

"The Ice Cream Man" is a heartwarming and humorous novel that follows the story of a beloved ice cream vendor who brings joy to the children of a small town. With his colorful truck and irresistible treats, he's a staple of summertime fun. But as the seasons change and the ice cream man faces challenges, he must confront his own demons and learn to adapt to a new reality. This poignant and uplifting tale explores themes of community, friendship, and the power of a simple pleasure.


Update Information

Change Log - Short description of recent changes

update.txt - Current HOMER configuration list (Currently support human hg17/hg18/hg19, mouse mm8/mm9, rat rn4, X. tropicalis xenTro2, drosophila dm3, and C. elegans ce6, Zebrafish danRer7, yeast sacCer2, Arabidopsis tair10, Rice msu6, Pombe ASM294v1)
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cbenner@ucsd.edu